1-O-Acetyl-2,3,5-tri-O-benzoyl-5(R)-C-methyl-D-ribo furanose

1-O-Acetyl-2,3,5-tri-O-benzoyl-5(R)-C-methyl-D-ribo furanose

• CAS Number: 72159-45-6
• UNSPSC Description: 1-O-Acetyl-2,3,5-tri-O-benzoyl-5(R)-C-methyl-D-ribo furanose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/1-o-acetyl-2-3-5-tri-o-benzoyl-5-r-c-methyl-d-ribo-furanose.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@@H](OC(C1=CC=CC=C1)=O)[C@@H]2[C@@H](OC(C3=CC=CC=C3)=O)[C@@H](OC(C4=CC=CC=C4)=O)C(OC(C)=O)O2
• Molecular Weight: 518.51
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported