5’-O-TBDPS-2,2’-anhydrouridine

5’-O-TBDPS-2,2’-anhydrouridine

• CAS Number: 175013-46-4
• UNSPSC Description: 5’-O-TBDPS-2,2’-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/5-o-tbdps-2-2-anhydrouridine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@@](OC(N2C=C3)=NC3=O)([H])[C@@]2([H])O[C@@H]1CO[Si](C4=CC=CC=C4)(C5=CC=CC=C5)C(C)(C)C
• Molecular Weight: 464.59
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported