5-(2-Hydroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine

5-(2-Hydroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine

• UNSPSC Description: 5-(2-Hydroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/5-2-hydroxyethyl-2-3-di-o-toluoyl-2-deoxyuridine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC=C(C)C=C1)OC[C@@H]2[C@@H](OC(C3=CC=C(C)C=C3)=O)C[C@H](N4C=C(CCO)C(NC4=O)=O)O2
• Molecular Weight: 508.52
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported