2′-Deoxy-2-iodoadenosine

• Description :

  2′-Deoxy-2-iodoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• UNSPSC :

  12352005

• Target :

  Nucleoside Antimetabolite/Analog

• Type :

  Oligonucleotides

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/2-deoxy-2-iodoadenosine.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC[C@@H]1[C@@H](O)C[C@H](N2C(N=C(I)N=C3N)=C3N=C2)O1

• Molecular Formula :

  C10H12IN5O3

• Molecular Weight :

  377.14

• References & Citations :

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Oligonucleotides

• Clinical Information :

  No Development Reported

• CAS Number :

  [118706-49-3]