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2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methoxyuridine

CAT:
804-HY-154083
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methoxyuridine - image 1

2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methoxyuridine

  • CAS Number: 2072145-81-2
  • UNSPSC Description: 2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
  • Target Antigen: Nucleoside Antimetabolite/Analog
  • Type: Oligonucleotides
  • Related Pathways: Cell Cycle/DNA Damage
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/2-o-acetyl-5-o-p-toluoyl-3-deoxy-3-fluoro-5-methoxyuridine.html
  • Solubility: 10 mM in DMSO
  • Smiles: F[C@H]1[C@@H](OC(C)=O)[C@H](N2C(NC(C(OC)=C2)=O)=O)O[C@@H]1COC(C3=CC=C(C)C=C3)=O
  • Molecular Weight: 436.39
  • References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported

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