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Vitamin D3-d7

CAT: 0804-HY-15398SSize: 500 µgDry Ice: YesHazardous: No
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CAT#:0804-HY-15398SSize:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vitamin D3-d7 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells[1][2].
CAS Number
1627523-19-6
UNSPSC
12352211
Hazard Statement
H300+H310, H372
Target
Bacterial; Endogenous Metabolite; Isotope-Labeled Compounds; VD/VDR
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Purity
97.00
Solubility
10 mM in DMSO|DMSO : 100mg/mL (ultrasonic)
Smiles
C=C1CC[C@@H](C/C1=C/C=C2[C@@]([H])([C@@]3(CCC/2)C)CC[C@]3([H])[C@@H](CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C)O
Molecular Formula
C27H37D7O
Molecular Weight
391.68
Precautions
H300+H310, H372
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Nazik Al-Hashimi, et al. Cholecalciferol|[3]Laura Bergadà, et al. Role of local bioactivation of vitamin D by CYP27A1 and CYP2R1 in the control of cell growth in normal endometrium and endometrial carcinoma. Lab Invest. 2014 Jun;94 (6) :608-22|[4]Hiroki Yoshioka, et al. Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice. PLoS One. 2017 Apr 27;12 (4) :e0176524.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light, stored under nitrogen
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported