Prexigebersen

CAT: 0804-HY-153495Size: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-153495Size:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Prexigebersen is an antisense oligonucleotide designed to inhibit protein synthesis of Grb2 (growth factor receptor bound protein 2) .

CAS Number

202484-91-1

Product Name Alternative

BP1001

UNSPSC

12352208

Target

ERK

Type

Oligonucleotides

Related Pathways

MAPK/ERK Pathway; Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/prexigebersen.html

Solubility

10 mM in H2O

Smiles

[Prexigebersen]

Molecular Formula

C177H224N63O110P17

Molecular Weight

5520.57

References & Citations

[1]Maro Ohanian, Tara L. Lin, Ellen Ritchie, et al. Pierce, Ana Tari Ashizawa, Hagop Kantarjian, Jorge E. Cortes, Gail J. Roboz; Safety and Efficacy of Lower Intensity Induction Therapy with Intravenous Prexigebersen (BP1001) in Patients with High-Risk and Relapsed/Refractory Acute Myeloid Leukemia (AML) . Blood 2021; 138 (Supplement 1) : 1281.|[2]Tremblay G, Khalafaghian G, Legault J, Nielsen P, Bartlett A. Dual ligation hybridization assay for the specific determination of oligonucleotide therapeutics. Bioanalysis. 2011;3 (5) :499-508.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

Phase 2

Prexigebersen

Popular Products