MEK-IN-6 (hydrate)

MEK-IN-6 (hydrate)

• CAS Number: 2845153-35-5
• UNSPSC Description: MEK-IN-6 hydrate (compound 69) is a MEK inhibitor. MEK-IN-6 hydrate has an IC50 of 2 nM for A375 cells[1].
• Target Antigen: MEK
• Type: Reference compound
• Related Pathways: MAPK/ERK Pathway
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mek-in-6-hydrate.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C=C2C(C(N(CC2)OCCO)=O)=C(N1C)NC3=CC=C(C=C3F)SC.O
• Molecular Weight: 411.45
• References & Citations: [1]Shelley Allen, et al. 3,4-dihydro-2,7-naphthyridine-1,6(2h,7h)-diones as mek inhibitors. WO2022208391A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported