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PRT3645

CAT: 0804-HY-153336Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153336Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PRT3645 (Example 20) is a CDK Inhibitor. CDK-IN-12 Inhibits CDK4/6 with IC50 values less than 20 nM[1].
CAS Number
2789680-97-1
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C3(CCCC3)N1C)SC(C4=C(F)C=NC(NC5=NC=C(C6CCN(CC6)C)C=C5)=N4)=C2
Molecular Formula
C26H29FN6OS
Molecular Weight
492.61
References & Citations
[1]Xiaowei Wu, et al. Cdk inhibitors and their use as pharmaceuticals. Patent WO2022133215.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK4; CDK6

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