Bemoradan

• Description :

  Bemoradan (compound 10a) is an orally active and selective canine Phosphodiesterase (PDE) fraction III inhibitor. Bemoradan is a long-acting, potent, inotropic vasodilator and a novel cardiotonic agent, and can be used in congestive heart failure research[1].

• CAS Number :

  [112018-01-6]

• UNSPSC :

  12352005

• Target :

  Phosphodiesterase (PDE)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/bemoradan.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1NN=C(C(C1)C)C2=CC3=C(NC(CO3)=O)C=C2

• Molecular Formula :

  C13H13N3O3

• Molecular Weight :

  259.26

• References & Citations :

  [1]Combs DW, et al. 6-Benzoxazinylpyridazin-3-ones: potent, long-acting positive inotrope and peripheral vasodilator agents. J Med Chem. 1990 Jan;33 (1) :380-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2