OICR12694

• Description :

  OICR12694 (JNJ-65234637) is an orally active inhibitor of B cell lymphoma 6 (BCL6) [1].

• Product Name Alternative :

  JNJ-65234637

• UNSPSC :

  12352005

• Target :

  Bcl-2 Family

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/oicr12694.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=C(N=C3N1CCC3)N(CC(NC4=C(Cl)C(F)=NC(N5[C@H](CN(CC5)C)C)=C4)=O)C=C2C6=CC(C(N)=O)=C(C(F)=C6F)O

• Molecular Formula :

  C29H28ClF3N8O4

• Molecular Weight :

  645.03

• References & Citations :

  [1]Mamai A, et al. Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor. ACS Med Chem Lett. 2023 Jan 12;14 (2) :199-210.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2360625-97-2]