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Anhydroleucovorin

CAT: 0804-HY-153039-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153039-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anhydroleucovorin is a form of tetrahydrofolate and is a substrate for cyclohydrolase, which converts it to 10-formyltetrahydrofolate. Anhydroleucovorin can be used for research in the field of tumors[1][2].
CAS Number
7444-29-3
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Field of Research
Others; Cancer
Assay Protocol
https://www.medchemexpress.com/anhydroleucovorin.html
Purity
96.60
Solubility
DMSO : 8.33 mg/mL (ultrasonic; adjust pH to 1 with 1 M HCL)
Smiles
O=C1C2=C(NC(N)=N1)NC[C@@]3([H])N2C=[N+](C4=CC=C(C=C4)C(N[C@H](C([O-])=O)CCC(O)=O)=O)C3
Molecular Formula
C20H21N7O6
Molecular Weight
455.42
Precautions
H315, H319
References & Citations
[1]M J OSBORN, et al. Participation of anhydroleucovorin in the hydroxymethyl tetrahydrofolic dehydrogenase system. Biochim Biophys Acta,1957,26, 3.|[2]K Motycka, et al. Localized chemotherapy of Gardner's lymphosarcoma of C3H mice using combinations of carrier-sorbed antifolics and detoxicating tetrahydrofolates. Czech Med,1981,4, 1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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