2′-Deoxy-8-(methylthio)adenosine

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804-HY-152996

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CAS Number: 29836-02-0
UNSPSC Description: 2′-Deoxy-8-(methylthio)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/2-deoxy-8-methylthio-adenosine.html
Solubility: 10 mM in DMSO
Smiles: OC[C@@H]1[C@@H](O)C[C@H](N2C(N=CN=C3N)=C3N=C2SC)C1
Molecular Weight: 295.36
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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