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Gemlapodect

CAT: 0804-HY-152838Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152838Size:1 Each
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Description
Gemlapodect (RO554965) is an inhibitor of phosphodiesterase 10A (PDE10A) . Gemlapodect can be used for researching schizophrenia[1].
CAS Number
1380329-87-2
Product Name Alternative
RO554965
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gemlapodect.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C(N2CCOCC2)=O)C=NN1C)NC3=CC4=NC(C5=CC=CC=C5)=NN4C=C3
Molecular Formula
C22H21N7O3
Molecular Weight
431.45
References & Citations
[1]Zagorska A, et al. Phosphodiesterase 10 Inhibitors - Novel Perspectives for Psychiatric and Neurodegenerative Drug Discovery. Curr Med Chem. 2018;25 (29) :3455-3481. |[2]GARIBALDI, et al. METHODS FOR THE TREATMENT OF CHILDHOOD-ONSET FLUENCY DISORDER. World Intellectual Property Organization. WO2022162193
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PDE10

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