N1-(1,1,1-Trifluoroethyl)pseudouridine

N1-(1,1,1-Trifluoroethyl)pseudouridine

• CAS Number: 1613529-80-8
• UNSPSC Description: N1-(1,1,1-Trifluoroethyl)pseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/n1-1-1-1-trifluoroethyl-pseudouridine.html
• Solubility: 10 mM in DMSO
• Smiles: FC(F)(F)CN(C(N1)=O)C=C([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C1=O
• Molecular Weight: 326.23
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported