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PP30

CAT: 0804-HY-15269Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-15269Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PP30, a TORKinib, is a potent, selective, and ATP-competitive inhibitor of mTOR with an IC50 of 80 nM.
CAS Number
1092788-09-4
UNSPSC
12352005
Target
MTOR; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pp30.html
Solubility
10 mM in DMSO
Smiles
NC1=C2C(N(C(C)C)N=C2C3=CC(C(NC4=NCCS4)=O)=CC=C3)=NC=N1
Molecular Formula
C18H19N7OS
Molecular Weight
381.45
References & Citations
[1]Morris E Feldman, et al. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol. 2009 Feb 10;7 (2) :e38.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kγ; PI3Kδ

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CatalogName
T28439-01PP30

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