2-Hydroxy-2’-deoxy-2’-fluoro-beta-D-arabino adenosine

2-Hydroxy-2’-deoxy-2’-fluoro-beta-D-arabino adenosine

• CAS Number: 899827-82-8
• UNSPSC Description: 2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/2-hydroxy-2-deoxy-2-fluoro-beta-d-arabino-adenosine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C(N)=NC(N3)=O)O[C@@H]1CO
• Molecular Weight: 285.23
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported