3’-O-(2-Methoxyethyl)-2-aminoadenosine

3’-O-(2-Methoxyethyl)-2-aminoadenosine

• CAS Number: 256224-02-9
• UNSPSC Description: 3’-O-(2-Methoxyethyl)-2-aminoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/3-o-2-methoxyethyl-2-aminoadenosine.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@@H]1[C@@H](OCCOC)[C@@H](O)[C@H](N2C(N=C(N)N=C3N)=C3N=C2)O1
• Molecular Weight: 340.34
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.|[2]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported