7-(2,3-Anhydro-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

CAT:

804-HY-152578

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UNSPSC Description:
7-(2,3-Anhydro-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen:
Nucleoside Antimetabolite/Analog
Type:
Oligonucleotides
Related Pathways:
Cell Cycle/DNA Damage
Applications:
Cancer-programmed cell death
Field of Research:
Others
Assay Protocol:
https://www.medchemexpress.com/7-2-3-anhydro-β-d-ribofuranosyl-7h-pyrrolo-2-3-d-pyrimidin-4-amine.html
Solubility:
10 mM in DMSO
Smiles:
OC[C@@H]1[C@@H](O2)[C@@H]2[C@H](N(C=C3)C4=C3C(N)=NC=N4)O1
Molecular Weight:
248.24
References & Citations:
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions:
Room temperature
Clinical Information:
No Development Reported
CAS Number:
40627-31-4

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