RLA-4842

CAT: 0804-HY-152512Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-152512Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RLA-4842 is an iron activator containing anti-androgen. RLA-4842 has anti-proliferative activity on metastatic castration-resistant prostate cancer (mCRPC) cell line[1].
UNSPSC
12352005
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rla-4842.html
Solubility
10 mM in DMSO
Smiles
CN(C(OC1=CC=C(C=C1)N2C(N(C(C23CCC3)=O)C4=CC(C(F)(F)F)=C(C=C4)C#N)=S)=O)CCN(C(O[C@@H]5CCC[C@@]6(OOC7(C8CC9CC(CC7C9)C8)O6)C5)=O)C
Molecular Formula
C42H46F3N5O8S
Molecular Weight
837.90
References & Citations
[1]Gonciarz RL, et al. Elevated labile iron in castration-resistant prostate cancer is targetable with ferrous iron-activatable antiandrogen therapy. Eur J Med Chem. 2023 Jan 14;249:115110.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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