RLA-4842

• Description :

  RLA-4842 is an iron activator containing anti-androgen. RLA-4842 has anti-proliferative activity on metastatic castration-resistant prostate cancer (mCRPC) cell line[1].

• UNSPSC :

  12352005

• Target :

  Androgen Receptor

• Type :

  Reference compound

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/rla-4842.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CN(C(OC1=CC=C(C=C1)N2C(N(C(C23CCC3)=O)C4=CC(C(F)(F)F)=C(C=C4)C#N)=S)=O)CCN(C(O[C@@H]5CCC[C@@]6(OOC7(C8CC9CC(CC7C9)C8)O6)C5)=O)C

• Molecular Formula :

  C42H46F3N5O8S

• Molecular Weight :

  837.90

• References & Citations :

  [1]Gonciarz RL, et al. Elevated labile iron in castration-resistant prostate cancer is targetable with ferrous iron-activatable antiandrogen therapy. Eur J Med Chem. 2023 Jan 14;249:115110.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported