3’-Beta-C-Methyl-N6-isopentenyl adenosine

3’-Beta-C-Methyl-N6-isopentenyl adenosine

• UNSPSC Description: 3’-Beta-C-Methyl-N6-isopentenyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/3-beta-c-methyl-n6-isopentenyl-adenosine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@](O)(C)[C@@H](CO)O[C@H]1N(C=N2)C3=C2C(NC/C=C(C)/C)=NC=N3
• Molecular Weight: 349.38
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.|[2]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported