H2N-PEG2-N3 (TosOH)

H2N-PEG2-N3 (TosOH)

• CAS Number: 2173092-98-1
• UNSPSC Description: H2N-PEG2-N3 (TosOH) is a click chemistry reagent containing an Azide. N3-PEG2-Amine is used as a Click-chemistry linker in various applications[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
• Target Antigen: ADC Linker
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/h2n-peg2-n3-tosoh.html
• Solubility: 10 mM in DMSO
• Smiles: [N-]=[N+]=NCCOCCOCCN.O=S(O)(C1=CC=C(C)C=C1)=O
• Molecular Weight: 346.40
• References & Citations: [1]Giraldo E, et al. A rationally designed self-immolative linker enhances the synergism between a polymer-rock inhibitor conjugate and neural progenitor cells in the treatment of spinal cord injury. Biomaterials. 2021 Sep;276:121052.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported