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Fmoc-DAP-N3

CAT: 0804-HY-151640Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151640Size:1 Each
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Description
Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
CAS Number
1021422-85-4
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/fmoc-dap-n3.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCCN=[N+]=[N-]
Molecular Formula
C18H18N4O2
Molecular Weight
322.36
References & Citations
[1] Chun-Chi Chen, et al. A mild removal of Fmoc group using sodium azide. Amino Acids. 2014 Feb;46 (2) :367-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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