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Phospholipid PL1

CAT: 0804-HY-151506-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-151506-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phospholipid PL1 is a phospholipid-derived nanoparticle, can deliver costimulatory receptor mRNA (CD137 or OX40) to T cells. Phospholipid PL1 could induce the activation of various immune cells, including T cells and dendritic cells (DCs) in order to boost antitumor immunity[1].
CAS Number
2274812-94-9
UNSPSC
12352200
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/phospholipid-pl1.html
Solubility
10 mM in DMSO
Smiles
O=C(CCCCCCCCN(CCCN(CCCCCCCCC(OC(CCCCC)CC)=O)CCCCCCCCC(OC(CCCCC)CC)=O)CCCOP(OCC)(OCC)=O)OC(CCCCC)CC
Molecular Formula
C61H121N2O10P
Molecular Weight
1073.59
References & Citations
[1]Li W, et al. Biomimetic nanoparticles deliver mRNAs encoding costimulatory receptors and enhance T cell mediated cancer immunotherapy. Nat Commun. 2021 Dec 14;12 (1) :7264.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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