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DHU-Se1

CAT: 0804-HY-151188Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151188Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DHU-Se1 is a potent anti-inflammatory agent. DHU-Se1 can stimulate macrophages to release the reactive selenium compound and reduce the expression of cellular inflammatory factors (eg: iNOS and TNF-α) . DHU-Se1 alleviate the process of inflammation by blocking the polarization of macrophages from M0 to M1[1].
UNSPSC
12352005
Target
NO Synthase; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dhu-se1.html
Solubility
10 mM in DMSO
Smiles
CN(C1=CC=C2C(SC3=C(N2C([Se]C4=CC=CC=C4)=O)C=CC(N(C)C)=C3)=C1)C
Molecular Formula
C23H23N3OSSe
Molecular Weight
468.47
References & Citations
[1]Peng H, et al. HOCl-Activated Reactive Organic Selenium Delivery Platform for Alleviation of Inflammation. Bioconjug Chem. 2022 Aug 26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
INOS

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