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Irampanel

CAT: 0804-HY-15082Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-15082Size:1 Each
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Description
Irampanel (BIIR 561) is an AMPA receptor and voltage-dependent sodium channel blocker. Irampanel inhibits kainate-induced currents in rat cortical neurons[1].
CAS Number
206260-33-5
Product Name Alternative
BIIR 561
UNSPSC
12352005
Target
IGluR; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/irampanel.html
Solubility
10 mM in DMSO
Smiles
CN(C)CCOC(C=CC=C1)=C1C2=NC(C3=CC=CC=C3)=NO2
Molecular Formula
C18H19N3O2
Molecular Weight
309.36
References & Citations
[1]Weiser T, et al. Characterization of the anticonvulsant and neuroprotectant BIIR 561 CL in vitro: effects on native and recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362 (4-5) :419-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

Alternative Products

CatalogName
T27626-01Irampanel
GTR19274108-01Irampanel hydrochloride

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