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RS6212

CAT: 0804-HY-150753-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-150753-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RS6212 is a specific LDH (lactate dehydrogenase) inhibitor with an IC50 value of 12.03 μM . RS6212 inhibits tumor growth and exhibits potent anticancer activity in multiple cancer cell lines[1].
CAS Number
2097925-52-3
UNSPSC
12352005
Target
Lactate Dehydrogenase; Oxidative Phosphorylation
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rs6212.html
Purity
98.86
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=C(CCC2)C2=NN1CC3CCN(C(C4=CC=CC=C45)=NS5(=O)=O)CC3
Molecular Formula
C20H22N4O3S
Molecular Weight
398.48
References & Citations
[1]Di Magno L, et al. Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment. Eur J Med Chem. 2022 Jul 14. 240:114605.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T61898-01RS6212