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SPR7

CAT: 0804-HY-150506Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-150506Size:1 Each
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Description
SPR7 (compound 7) is a potent and selective rhodesain inhibitor, with a Ki of 0.51 nM. SPR7 shows antiparasitic activity against T. b. brucei, with an EC50 of 1.65 μM[1].
CAS Number
3032859-14-3
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/spr7.html
Solubility
10 mM in DMSO
Smiles
O=C(C)/C=C/[C@@H](NC([C@@H](NC(NC(C(C)=C1)=CC=C1Cl)=O)CC2=CC=CC=C2)=O)CCC3=CC=CC=C3
Molecular Formula
C30H32ClN3O3
Molecular Weight
518.05
References & Citations
[1]Santo Previti, et al. Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain. ACS Med. Chem. Lett. 2022
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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