TSPO ligand-3
CAT:
804-HY-150410
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TSPO ligand-3
- CAS Number: 2241669-89-4
- UNSPSC Description: TSPO ligand-3 is a ligand of AUTAC2. AUTAC2 contains an p-fluorobenzylguanine (FBnG) and an synthetic ligand of FKBP (SLF) moiety, which can cause significant silencing of FKBP12 in HeLa cells[1].
- Target Antigen: AUTACs
- Type: Reference compound
- Related Pathways: Autophagy;PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tspo-ligand-3.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1N(CCCC1)C(C(C(C)(C)CC)=O)=O)O[C@@H](C2=CC(NC(CCC(O)=O)=O)=CC=C2)CCC3=CC(OC)=C(C=C3)OC
- Molecular Weight: 624.72
- References & Citations: [1]Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported