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Zavabresib

CAT: 0804-HY-150268Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-150268Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zavabresib (BET-IN-16) (Compound I) is a BET inhibitor. BET-IN-16 shows anticancer activity. Zavabresib inhibits prostate cancer cell growth, with IC50 values of 0.043 and 0.034 μM against LNCaP and 22Rv1 cells, respectively[1].
CAS Number
2089390-09-8
Product Name Alternative
BET-IN-16
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bet-in-16.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C2=CN(C(C3=NC=CC=C3)(C)C4=NC=CC=C4)C5=C2N=CC(C6=C(C)ON=C6C)=C5)C=C1)O
Molecular Formula
C31H25N5O3
Molecular Weight
515.56
References & Citations
[1]Ben Powell, et al. Combinational drug anticancer therapies. Patent, WO2022040512A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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