SLB1122168

• Description :

  SLB1122168 is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM[1].

• UNSPSC :

  12352005

• Target :

  LPL Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/slb1122168.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCCCCCCCCCC1=CC=C2C(OC(NC[C@@H]3CNCC3)=N2)=C1.Cl

• Molecular Formula :

  C22H36ClN3O

• Molecular Weight :

  393.99

• References & Citations :

  [1]Ariel L Burgio, et al. 2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) . J Med Chem. 2023 Apr 27;66 (8) :5873-5891.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2999629-17-1]