SLB1122168

• Description:

  SLB1122168 is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM[1].

• UNSPSC:

  12352005

• Target:

  LPL Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/slb1122168.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCCCCCCCC1=CC=C2C(OC(NC[C@@H]3CNCC3)=N2)=C1.Cl

• Molecular Formula:

  C22H36ClN3O

• Molecular Weight:

  393.99

• References & Citations:

  [1]Ariel L Burgio, et al. 2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) . J Med Chem. 2023 Apr 27;66 (8) :5873-5891.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2999629-17-1