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SLB1122168

CAT: 0804-HY-150254Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-150254Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SLB1122168 is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM[1].
CAS Number
2999629-17-1
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/slb1122168.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCC1=CC=C2C(OC(NC[C@@H]3CNCC3)=N2)=C1.Cl
Molecular Formula
C22H36ClN3O
Molecular Weight
393.99
References & Citations
[1]Ariel L Burgio, et al. 2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) . J Med Chem. 2023 Apr 27;66 (8) :5873-5891.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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