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BK50164

CAT: 0804-HY-150048Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-150048Size:1 Each
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Description
BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 μM. BK50164 binds to CD99 with a KD value of 1.5 μM. BK50164 shows antiproliferative activity. BK50164 induced Apoptosis and cell cycle arrest at Sub-G1 phase[1].
CAS Number
2204291-78-9
UNSPSC
12352005
Target
Apoptosis; CD73
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bk50164.html
Solubility
10 mM in DMSO
Smiles
NC1=NC(Cl)=NC2=C1N=CN2[C@@H]3O[C@H](COC(C(O)=O)C(O)=O)[C@@H](O)[C@@H]3F
Molecular Formula
C13H13ClFN5O7
Molecular Weight
405.72
References & Citations
[1]Roland Joseph Billedeau, et al. Ectonucleotidase inhibitors and methods of use thereof. WO2018119284A1.|[2]Balaraman K, et al. Design, synthesis and biological evaluation of Nucleosidic CD99 inhibitors that selectively reduce Ewing sarcoma viability. Eur J Med Chem. 2023 May 5;251:115244.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T74865-01BK50164

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