Products for Research Use Only
RegisterLogin

DS43260857

CAT: 0804-HY-149994Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-149994Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DS43260857 is a potentNaV1.7inhibitor, which has a high inhibitory effect on both human and mouse NaV1.7. The IC50 values of DS43260857 for hNaV1.1, hNaV1.5, hNaV1.7, mNaV1.7 are 6.6, 14, 0.015 and 0.061 μM, respectively[1].
CAS Number
1612158-07-2
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ds43260857.html
Solubility
10 mM in DMSO
Smiles
CC1=CN(C2=CC(C(F)(F)F)=CN=C2)C3=C1C=C(C(NS(C4CC4)(=O)=O)=O)C=C3
Molecular Formula
C19H16F3N3O3S
Molecular Weight
423.41
References & Citations
[1]Narayan Karanjule, et al. N-Aryl Indoles as a Novel Class of Potent NaV1.7 Inhibitors. ACS Med Chem Lett. 2023 May 24;14 (6) :788-793.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19235465-01DS43260857

Popular Products