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8BTC

CAT: 0804-HY-149818Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149818Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
8BTC (compound 4w) is a potent covalent Notum inhibitor with IC50 of 2.5 nM[1].
CAS Number
3064070-24-9
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8btc.html
Solubility
10 mM in DMSO
Smiles
CC(N1CCC2=C1C=CC(Cl)=C2Cl)=O
Molecular Formula
C10H9Cl2NO
Molecular Weight
230.09
References & Citations
[1]Benjamin N Atkinson, et al. Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity. Eur J Med Chem. 2023 May 5;251:115132.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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