Phosphodiesterase-IN-1

Phosphodiesterase-IN-1

• CAS Number: 521297-42-7
• UNSPSC Description: Phosphodiesterase-IN-1 (Compound 7) is a phosphodiesterase (PDE) inhibitor with anti-Plasmodium activity. Phosphodiesterase-IN-1 has antiproliferative activity against P. falciparum (strain 3D7) with an IC50 value of 0.64 μM[1].
• Target Antigen: Parasite; Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/phosphodiesterase-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N=C(CC2=CC=C(C=C2)F)NC3=C1NN=C3C(C)C
• Molecular Weight: 286.30
• References & Citations: [1]Howard BL, et al. Identification of potent phosphodiesterase inhibitors that demonstrate cyclic nucleotide-dependent functions in apicomplexan parasites. ACS Chem Biol. 2015 Apr 17;10(4):1145-54.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported