CMX990

CAT: 0804-HY-149767-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-149767-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

CMX990 is a SARS-CoV-2 3CL protease inhibitor. The EC90s for inhibiting SARS-CoV-2 were 9.6 nM and 101 nM in human bronchial epithelial cells (HBECs) and HeLa-ACE2 cells, respectively. CMX990 has good ADME and pharmacokinetic properties[1].

CAS Number

2882934-64-5

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cmx990.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@H](C(COC(F)(F)F)=O)C[C@@H]1CCNC1=O)[C@@H]2CC3(CC3)CN2C([C@H](O)CC(C)C)=O

Molecular Formula

C22H32F3N3O6

Molecular Weight

491.50

References & Citations

[1]Zhang FM et al. Discovery of highly potent covalent SARS-CoV-2 3CLpro inhibitors bearing 2-sulfoxyl-1,3,4-oxadiazole scaffold for combating COVID-19. Eur J Med Chem. 2023 Nov 15;260:115721.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-162094	CMX410

Alternative Products

Catalog	Name
T86068-01	CMX990

CMX990

Related Products

Alternative Products

Popular Products