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Spermatinamine

CAT: 0804-HY-149712Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149712Size:1 Each
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Description
Spermatinamine is a novel alkaloid with a bromotyrosyl-spermine-bromotyrosyl sequence, and a natural ICMT inhibitor. Spermatinamine can be isolated from the Australian sponge Pseudoceratina[1].
CAS Number
1001438-81-8
UNSPSC
12352005
Target
ICMT
Type
Natural Products
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/spermatinamine.html
Solubility
10 mM in DMSO
Smiles
BrC1=C(OC)C(Br)=CC(C/C(C(NCCCN(C)CCCCN(C)CCCNC(/C(CC2=CC(Br)=C(OC)C(Br)=C2)=N/O)=O)=O)=N\O)=C1
Molecular Formula
C32H44Br4N6O6
Molecular Weight
928.34
References & Citations
[1]Buchanan MS et al. Spermatinamine, the first natural product inhibitor of isoprenylcysteine carboxyl methyltransferase, a new cancer target. Bioorg Med Chem Lett. 2007 Dec 15;17 (24) :6860-3.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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