HD-2a

• Description:

  HA-2a can inhibit the JAK2/STAT3 pathway via downregulates circDcbld2 expression in RAW264.7 cells[1].

• UNSPSC:

  12352005

• Target:

  JAK; STAT

• Type:

  Reference compound

• Related Pathways:

  Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/hd-2a.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(O)C=C(OCC)C=C2O[C@H](C3=CC(O)=C(C=C3)OC)C1

• Molecular Formula:

  C18H18O6

• Molecular Weight:

  330.33

• References & Citations:

  [1]Sanu Karan, et al. Hypoxia-Directed and Self-Immolative Theranostic Agent: Imaging and Treatment of Cancer and Bacterial Infections. J Med Chem. 2023, 66, 20.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [606148-05-4]