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Phosphatase-IN-1

CAT: 0804-HY-149492-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-149492-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phosphatase-IN-1 (compound II-8), a propranolol derivative, is a phosphatidate phosphatase (Pah) inhibitor. Phosphatase-IN-1 can binds to MoPah1, with an affinity constant of 19.8 μM. Phosphatase-IN-1 inhibits growth of plant pathogens and shows anti-fungal ability. Phosphatase-IN-1 is not toxic to rice seedlings and wheat heads[1].
CAS Number
2889356-55-0
UNSPSC
12352005
Target
Fungal; Phosphatase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/phosphatase-in-1.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(CNCC(COC2=CC=C(C=C2Cl)Cl)O)C=C1
Molecular Formula
C16H16Cl2FNO2
Molecular Weight
344.21
References & Citations
[1]Zhao J, et al. Identification of propranolol and derivatives that are chemical inhibitors of phosphatidate phosphatase as potential broad-spectrum fungicides. Plant Commun. 2023 Aug 30:100679.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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