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AJH-836

CAT: 0804-HY-149490Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149490Size:1 Each
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Description
AJH-836 is an activator of Munc13-1 and PKC ε/α (Kd: 4.5 nM for PKCα) . AJH-836 triggers the translocation of Munc13-1 from the cytoplasm to the plasma membrane. AJH-836 can be used for research of neurodegenerative diseases[1].
CAS Number
[388621-67-8]
UNSPSC
12352005
Target
PKC
Type
Reference compound
Related Pathways
Epigenetics; TGF-beta/Smad
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ajh-836.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C)C(OCC(C/C1=C\CC(CC(C)C)CC(C)C)(CO)OC1=O)=O
Molecular Formula
C22H38O5
Molecular Weight
382.53
References & Citations
[1]Das J, Yet al. Activation of Munc13-1 by Diacylglycerol (DAG) -Lactones. Biochemistry. 2023 Aug 31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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