AJH-836

• Description:

  AJH-836 is an activator of Munc13-1 and PKC ε/α (Kd: 4.5 nM for PKCα) . AJH-836 triggers the translocation of Munc13-1 from the cytoplasm to the plasma membrane. AJH-836 can be used for research of neurodegenerative diseases[1].

• UNSPSC:

  12352005

• Target:

  PKC

• Type:

  Reference compound

• Related Pathways:

  Epigenetics; TGF-beta/Smad

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ajh-836.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC (C) (C) C (OCC (C/C1=C\CC (CC (C) C) CC (C) C) (CO) OC1=O) =O

• Molecular Formula:

  C22H38O5

• Molecular Weight:

  382.53

• References & Citations:

  [1]Das J, Yet al. Activation of Munc13-1 by Diacylglycerol (DAG) -Lactones. Biochemistry. 2023 Aug 31.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  388621-67-8