Yhhu6669

CAT: 0804-HY-149357Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-149357Size:1 Each

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Description

Yhhu6669 is an anti-HBV agent. Yhhu6669 inhibits HBV DNA. Yhhu6669 inhibits HBV replication by inducing the formation of DNA-free capsids. Yhhu6669 decreases HBV DNA and HBcAg in AAV/HBV-infected mice. Yhhu6669 has favorable PK properties[1].

CAS Number

2569526-80-1

UNSPSC

12352005

Target

HBV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/yhhu6669.html

Solubility

10 mM in DMSO

Smiles

ClC1=C(NCCCOC([C@@H](N)C(C)C)=O)N=C(F)C(C(C2=C3C=CC=C2)=NN(CC4=CC=C(C#N)C=C4)C3=O)=C1

Molecular Formula

C29H28ClFN6O3

Molecular Weight

563.02

References & Citations

[1]Chen W, et al. A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B. Eur J Med Chem. 2023 Sep 5;257:115485.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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