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PhoBET1

CAT: 0804-HY-149328Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149328Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PhoBET1 is a photocaged-PROTAC. phoBET1 can achieve BRD4 degradation and effectively suppress tumor growth[1].
CAS Number
3033545-34-2
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/phobet1.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(C(OCN(C(CCC2N3C(C4=CC=CC(OCC(NCCCCNC(C[C@H]5C6=NN=C(N6C7=C(C(C8=CC=C(C=C8)Cl)=N5)C(C)=C(C)S7)C)=O)=O)=C4C3=O)=O)=O)C2=O)C)=C(C=C1OCC(NCCN)=O)[N+]([O-])=O
Molecular Formula
C52H56ClN11O13S
Molecular Weight
1110.58
References & Citations
[1]He Q, et al. Near-Infrared-Activatable PROTAC Nanocages for Controllable Target Protein Degradation and On-Demand Antitumor Therapy. J Med Chem. 2023 Jun 6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T81486-01PhoBET1

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