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PYZ18

CAT: 0804-HY-149299Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149299Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PYZ18 is a selective COX-2 inhibitor with an IC50 of 7.07 μM. PYZ18 is the best lead compound for COX-2 inhibitors. PYZ18 has anti-inflammatory and other biological properties[1].
CAS Number
1447578-01-9
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pyz18.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=NN(C(C2=CC=C(C)C=C2)=C1)C3=CC=C(C(N)=S)C=C3)F
Molecular Formula
C18H14F3N3S
Molecular Weight
361.38
References & Citations
[1]Chahal S, et al. Design and Development of COX-II Inhibitors: Current Scenario and Future Perspective. ACS Omega. 2023 May 9;8 (20) :17446-17498
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2

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