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AMX12006

CAT: 0804-HY-149290-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-149290-01Size:1 mg
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Description
AMX12006 is a potent, selective and orally active EP4 antagonist with an IC50 value of 4.3 nM. AMX12006 shows cytotoxic and antitumor activity[1].
CAS Number
2639775-01-0
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amx12006.html
Purity
99.9
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](C)C1=CC=C(C(O)=O)C=C1)C2=C(C3=CC=CC=C3N2C)NC4=CC(C(F)(F)F)=CC=C4
Molecular Formula
C26H22F3N3O3
Molecular Weight
481.47
References & Citations
[1]Debasis Das, et al. Discovery of Novel, Selective Prostaglandin EP4 Receptor Antagonists with Efficacy in Cancer Models. ACS Med. Chem. Lett. 2023.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP

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CatalogName
T78710-01AMX12006

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