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TSC26

CAT: 0804-HY-149073Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149073Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TSC26, a thiosemicarbazone, is a potent cruzipain (CZP) inhibitor with an IC50 of 175 nM, a pIC50 of 6.76 and a pKa of 6.6. TSC26 has the potential for parasitic diseases research[1].
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tsc26.html
Solubility
10 mM in DMSO
Smiles
NC(N/N=C(C1=CC=C(C(Cl)=C1)Cl)\CCN2C=CN=C2)=S
Molecular Formula
C13H13Cl2N5S
Molecular Weight
342.25
References & Citations
[1]Gabriel Jasinski, et al. Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors. Eur J Med Chem. 2023 Apr 7;254:115345.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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