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Vabametkib

CAT: 0804-HY-148803-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148803-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vabametkib is a potent inhibitor of hepatocyte growth factor receptor (HGFR) . Vabametkib inhibits Hs746T cells proliferation and inhibits c-Met with an IC50 value of 7 nM. Vabametkib can be used as an antineoplastic agent[1][2].
CAS Number
1571903-56-4
UNSPSC
12352005
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vabametkib.html
Solubility
10 mM in DMSO
Smiles
CN(N=C1)C=C1C2=CN=C(N=N3)C(N3C[C@@H]4CN(C5=NC=C(C6=CC=C(C=C6)CN7CCN(CC7)C)C=N5)CCO4)=N2
Molecular Formula
C29H34N12O
Molecular Weight
566.66
References & Citations
[1]WHO Drug Informat ion - World Health Organization (WHO) .|[2]Jung Hui Jeong, et al. Preparation of triazolopyrazine derivatives as c-Met kinase inhibitors: Korea, Republic of, KR2014022229. 2014-02-24.|[3]WHO Drug Information-World Health Organization (WHO) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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CatalogName
T70434-01Vabametkib

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