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Demethyl bleomycin A2

CAT: 0804-HY-148649-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148649-01Size:1 mg
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Description
Demethyl bleomycin A2 is a Bleomycin congener. The DNA cleavage of demethyl bleomycin A2 is insensitive to the presence of 5-Methylcytidine (HY-113135).
CAS Number
41089-03-6
UNSPSC
12352005
Target
Antibiotic
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/demethyl-bleomycin-a2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC2=NC(C3=NC(C(NCCCSC)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O[C@@H]6[C@H]([C@H]([C@@H]([C@H](O6)CO)O)OC(N)=O)O
Molecular Formula
C54H81N17O21S3
Molecular Weight
1400.52
References & Citations
[1]Hertzberg RP, et al. Degradation of structurally modified DNAs by bleomycin group antibiotics. Biochemistry. 1988 May 3;27 (9) :3164-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported