RL-0070933

• Description:

  RL-0070933 is a potent smo cilial modulator with an EC50 value of 0.02 µM. RL-0070933 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319

• Target:

  Hedgehog; Smo

• Type:

  Reference compound

• Related Pathways:

  Stem Cell/Wnt

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/rl-0070933.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N/N=C/C1=CC=C(C2=CC=CC=C2)C=C1)C3=CC=C(O)C=C3

• Molecular Formula:

  C20H16N2O2

• Molecular Weight:

  316.35

• Precautions:

  P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

• References & Citations:

  [1]Yu Wang, et al. Modulators of hedgehog signaling pathway. US20130274233A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [301326-41-0]