UHMCP1 (dihydrochloride)

• UNSPSC Description:

  UHMCP1 dihydrochloride is a potent UHM domain splicing inhibitor with a Kd value of 79 μM. UHMCP1 dihydrochloride prevents the SF3b155/U2AF65 interaction. UHMCP1 dihydrochloride impacts cell viability and RNA splicing[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/uhmcp1-dihydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(N(C[C@]1([H])CC2)C[C@]2([H])[C@H]1N)CCC3=CNC4=CC=CC=C34.[H]Cl.[H]Cl

• Molecular Weight:

  370.36

• References & Citations:

  [1]Kobayashi A, et al. Identification of a small molecule splicing inhibitor targeting UHM domains. FEBS J. 2022 Feb;289(3):682-698.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2925647-93-2