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4-Methoxyestradiol

CAT: 0804-HY-148296Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148296Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4-Methoxyestradiol is methoxylestradiol that induces oxidative DNA damage in human lung epithelial cells. 4-Methoxyestradiol also elevates ROS and SOD activities in H1355 cells[1].
CAS Number
26788-23-8
UNSPSC
12352005
Target
DNA/RNA Synthesis; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-methoxyestradiol.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C(OC)=C4CC3
Molecular Formula
C19H26O3
Molecular Weight
302.41
References & Citations
[1]Yahsin Cheng, et al. 4-Methoxyestradiol-induced oxidative injuries in human lung epithelial cells. Toxicol Appl Pharmacol. 2007 May 1;220 (3) :271-7.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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